The Long-Acting One
Up to 36 hours of clinical activity, which is what distinguishes tadalafil from the shorter-acting PDE5 inhibitors.

Tadalafil 20mg — generic Cialis — the long-acting PDE5 inhibitor, with a window of up to 36 hours. Prescribed by a licensed provider, dispensed by a licensed U.S. pharmacy in the OLIV Well network, and handled entirely online.
Products are prescribed by licensed telehealth providers and fulfilled through FDA-registered, 503A-compliant compounding pharmacies. These statements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease. Results may vary.
Tadalafil is a PDE5 inhibitor. It blocks the phosphodiesterase type 5 enzyme, which promotes smooth muscle relaxation in the penile vasculature and increases blood flow in response to sexual stimulation. It does not work without sexual stimulation. What separates tadalafil from the shorter-acting members of its class is duration: it stays clinically active for up to 36 hours, which is why it is often described as removing the need to time a dose to a specific moment. Food does not meaningfully affect its absorption.
Tadalafil received FDA approval for erectile dysfunction in 2003 and belongs to the PDE5 inhibitor class, which has been studied in thousands of clinical trials across a broad range of patient populations. Integrated analyses of the tadalafil trial programme pooled results across those populations. The generic form contains the same active ingredient as the branded product.
Potential side effects include headache, flushing, nasal congestion, dyspepsia (indigestion), back pain and muscle aches, and dizziness or lightheadedness. Serious but less common effects can include sudden vision or hearing loss and priapism — a prolonged, painful erection requiring immediate medical attention. Tadalafil is contraindicated in patients taking nitrates or certain alpha-blockers and in patients with specific cardiovascular conditions. This is not a complete list. Your OLIV Well provider will review your health history before prescribing and will identify any contraindications specific to your situation.
Function: By inhibiting PDE5, tadalafil promotes vasodilation and supports the physiological conditions required for erectile function in response to stimulation, across a longer active window than the short-acting members of its class. Benefit: Sexual health is one of the most common and least discussed areas of men's health. Telehealth removes the conversation nobody wants to have in person and gives you access to a well-established, well-documented treatment prescribed by a real provider. The whole process stays private.
Pooled analysis of tadalafil clinical trials across a broad range of patient populations.
Read StudyOverview of PDE5 inhibitor mechanism and its clinical application.
Read StudyThese statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. OLIV Well is not a pharmacy. Prescriptions are written by licensed telehealth providers and fulfilled by FDA-registered, 503A-compliant compounding pharmacies. Results may vary. Consult a licensed healthcare provider before starting any treatment.
Up to 36 hours of clinical activity, which is what distinguishes tadalafil from the shorter-acting PDE5 inhibitors.
FDA-approved for erectile dysfunction since 2003, with integrated analyses pooling results across many patient populations.
Your intake, your prescription, and your shipment stay between you and your provider. Discreet packaging, discreet process.
Dispensed by a licensed U.S. pharmacy in the OLIV Well network — not a supplement company, not an online supplement store.
It contains the same active ingredient. Tadalafil is the active in Cialis, and the generic is an FDA-approved equivalent held to the same standards for the active ingredient, strength and quality.
Both are PDE5 inhibitors. The practical difference is duration: sildenafil is taken 30 to 60 minutes before activity and works over a few hours, while tadalafil stays active for up to 36 hours. Food also affects sildenafil more than tadalafil.
Tadalafil 20mg is a single-ingredient generic. The compounded Tadalafil formulation on this site combines tadalafil with two additional actives in one preparation. Your OLIV Well provider will recommend which is appropriate based on your intake.
Yes. Tadalafil is contraindicated with nitrates, certain alpha-blockers, and in patients with specific cardiovascular conditions. Your OLIV Well provider reviews your complete health history before prescribing. Do not start this treatment without a provider evaluation.
If your intake doesn't result in an approved prescription, no charge is applied.
Answer a short health questionnaire online. No appointment, no waiting room — just honest answers from the comfort of wherever you are.
A licensed telehealth provider reviews your intake and, if appropriate, writes your prescription. The same standard of care as an in-person visit, without the trip.
Your treatment ships from an FDA-registered, 503A-compliant compounding pharmacy — discreetly packaged and delivered fast.
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Take the first step online, in under ten minutes. A licensed provider reviews your intake — and if it's a fit, your treatment ships fast.